Integrated Biobank for Space Life Science

release November 26, 2020 (JST)

Overview

JAXA Biorepository at Tsukuba Space Center

The Integrated Biobank for Space Life Science (ibSLS) is a database of multi-omics data, including transcriptome, metabolome, and phenotypes obtained from mouse habitat missions conducted by the Japan Aerospace Exploration Agency (JAXA). The JAXA Tsukuba Space Center stores over 600 biospecimens remaining from spaceflight investigations conducted since 2016. Biospecimens are available on request first to Japanese investigators, then to those in the USA under the Japan-US Open Platform Partnership Program (JP-US OP3). The missions utilized a mouse experimental system for space flight, referred to as Mouse Habitat Unit (MHU), in order to achieve the return of live mice.

As of November 2020, five MHU missions shown below have been conducted.

Projects

Themes Principal Investigator(s)

Launch Vehicle

MHU-1

ISS Research Explorer

Mouse Epigenetics

Satoru Takahashi, M.D., Ph.D.
Prof. of Univ. of Tsukuba

SpX-9

MHU-2

ISS Research Explorer

Multi Omics Mice

Hiroshi Ohno, M.D., Ph.D.
Team Leader of RIKEN

SpX-12

Medical Proteomics

Hisashi Hirano, Ph.D.
Prof. of Gunma Paz Univ.

MHU-3

ISS Research Explorer

Mouse Stress Defense

Masayuki Yamamoto, M.D., Ph.D.
Prof. of Tohoku Univ.

SpX-14

MHU-4

Gravity Gateway Reflex

Masaaki Murakami, V.M.D., Ph.D.
Prof. of Hokkaido Univ.

SpX-17

ISS Research Explorer

JAXA Moon-G mission (1)

Dai Shiba, Ph.D.
Manager of JAXA

MHU-5

ISS Research Explorer

JAXA Moon-G mission (2)

Dai Shiba, Ph.D.
Manager of JAXA

SpX-20

Database of multi omics data

【ToMMo web】ibSLS

JAXA Biospecimens Sharing Program (Japanese and US Investigators only)

JAXA Biospecimens Sharing Program (BSP) is for Japanese and US Investigators*.

* Japanese national or US national, resident in the territory of Japan or the USA

The process is following;

First, please check the "Tissue List", "Biospecimen Request Form" and "Material Transfer Agreement (MTA)" before your request. Investigators who want to request biospecimens must input the information of your previous works including the peer review papers that you were the corresponding author(s). This is used for the confirmation of your affiliation and email address. The biospecimens shall be provided at no cost for its preparation except for the distribution costs (shipping fee), therefore please ask shipping company about tentative the shipping fee from JAXA (Tsukuba, Ibaraki, Japan) to your institute in advance.

Second, please submit the PDF version of "Biospecimen Request Form" with your signature to JAXA by email ( ). JAXA will check the sheet and return our answer to you with the further process.

Third, after the finalization of MTA between JAXA and your institute, biospecimens will be shipped to your institute.

タイトル	サイズ	ID
【ibSLS】Tissue List	[ pdf: 579.2 KB]	72096
【ibSLS】Biospecimen Request Form	[ docx: 50.2 KB]	72097
【ibSLS】Material Transfer Agreement (MTA)	[ pdf: 167.0 KB]	72098

Citing ibSLS

Please cite Suzuki T. et al. Commun Biol 3, 496 (2020) and Afshinnekoo E. et.al Cell (2020) for the publication of the analysis using the data from ibSLS.